Vitex agnus-castus (Chasteberry) and PMS: Can Nature Support Your Hormonal Health?

At Sirona Health, we know how much hormonal health affects every aspect of your wellbeing. Many women we see struggle with premenstrual symptoms, or the more severe form known as Premenstrual Dysphoric Disorder (PMDD). If you’ve been feeling that your mood, energy, and daily life are being disrupted every month, you are not alone—and there are solutions.

One herbal remedy that has been studied in women’s health for centuries is Vitex agnus-castus, also known as chasteberry. But how effective is it really, and could it help you?

What is Vitex agnus-castus?

Vitex agnus-castus is a fruit extract from the chaste tree, traditionally used for women’s reproductive health. Today, modern research has explored its role in:

  • Reducing PMS and PMDD symptoms

  • Supporting cycle regularity

  • Helping with hormonal balance

Its popularity comes from being a natural option for women who want to avoid—or complement—conventional treatments such as antidepressants or hormonal contraceptives.

How might Vitex help PMDD?

PMS is thought to result from heightened sensitivity to normal hormonal changes in the menstrual cycle. Vitex appears to work by:

  • Balancing hormones: It may lower prolactin levels through its effect on dopamine, helping regulate the menstrual cycle.

  • Supporting mood: Some of its plant compounds may positively influence neurotransmitters like serotonin, which plays a key role in PMS.

  • Easing physical symptoms: Women in clinical trials reported improvement in breast tenderness, bloating, headaches, and fatigue.

What does the evidence say?

Research—including studies reviewed by the European Medicines Agency—suggests that standardised Vitex extracts can significantly reduce PMS and PMDD symptoms when taken consistently for at least 3 months.

Women using Vitex in clinical trials reported:

  • Less irritability, mood swings, and anger

  • Reduced breast pain and bloating

  • Improved overall sense of wellbeing

Importantly, Vitex is generally well tolerated, with mild side effects such as nausea or headache in a small number of women.

Should you try Vitex for PMS?

Vitex may be a good option if:

  • You prefer a natural, evidence-based approach

  • You’ve tried lifestyle changes but still struggle with symptoms

  • You want to explore alternatives or add-ons to conventional medication

But, as with all herbal medicines, it’s not right for everyone. Its safety can depend on your medical history, medications, and whether you are trying for pregnancy.

This is where a consultation with a doctor who understands both conventional and holistic options is invaluable. At Sirona Health, we help women choose the best treatment path—whether that’s herbal support, prescription medication, or a combination of approaches.

How Sirona Health can help

At Sirona Health, our goal is to give you clarity and control over your hormonal health. Through our specialist services, we can help you understand whether Vitex—or another treatment—might work best for your body.

We offer focused support for issues such as PMS, PMDD, perimenopause, and hormonal health.

Together, we’ll create a plan that’s tailored to you.

Next steps

If PMS is affecting your quality of life, you don’t have to keep struggling. There are safe and effective ways forward—and you deserve expert support.

FAQ

  • Vitex agnus-castus, also known as chasteberry, is a herbal extract from the fruit of the chaste tree. It has been traditionally used for women’s hormonal health, especially for PMS and cycle regulation.

  • Research suggests that standardised Vitex extracts can reduce both physical and emotional symptoms of PMDD, such as irritability, low mood, breast tenderness, and bloating. It may not work for everyone, but many women notice improvement after 2–3 months of consistent use.

  • Vitex may reduce prolactin levels by acting on dopamine pathways and influence hormones linked to the menstrual cycle. This can help balance mood and ease physical premenstrual symptoms.

  • Most studies show that women need to take Vitex daily for at least 3 menstrual cycles to notice benefits.

  • Vitex is generally well tolerated, but mild side effects like nausea or headache can occur. It may not be suitable if you are pregnant, breastfeeding, or taking certain medications. Always seek medical advice before starting.

  • That depends on your individual health needs. Some women use Vitex alongside lifestyle changes or prescribed medications. At Sirona Health, we’ll help you find the right approach for your body

  • Yes, we recommend it. Even natural remedies can interact with other medicines or health conditions. Our Women’s Health Consultations ensure any treatment is safe and tailored to you.

About the Author

Dr Georgina Standen is a Women’s Health GP and Medical Director of Sirona Health. She specialises in the diagnosis and treatment of PMS (premenstrual syndrome) and PMDD (premenstrual dysphoric disorder), as well as broader hormonal health and menopause care. Her approach blends evidence-based medicine with personalised, compassionate support to help women regain control of their health and wellbeing.

Sirona Health offers PMS and PMDD consultations in Stroud, Cirencester, Tetbury, Fairford, Lechlade, Calne, Corsham, Chippenham, Malmesbury and Bath, along with nationwide secure online appointments.

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