Methylation, the MTHFR Gene, and PMDD: What’s the Connection?

Could your genes and folate metabolism influence your premenstrual mood? New research suggests that the MTHFR gene — which affects how we process folate and regulate brain chemistry — may play a role in PMS and PMDD. Dr Georgina Standen explains what methylation is, what the latest studies show, and how to support healthy folate levels through diet and supplements.