Group B Streptococcus in pregnancy
Group B Streptococcus can colonisation the vagina or rectum in up to a quarter of pregnant women and in a small proportion of these it will cause infection in the baby. Only a small number of women can be tested on the NHS but at Sirona Health you can decide to test privately and have a detailed discussion about how to manage the result.
Iodine deficiency
Iodine is an essential mineral which is especially important for women considering pregnancy, during pregnancy and during breastfeeding
Progesterones and meningiomas
Recent studies have highlighted a potential link between certain progesterone-based medications and an increased risk of meningiomas, which are typically benign brain tumors. While these tumors are more common in women and often asymptomatic, some high-dose progestogens—such as medroxyprogesterone acetate (found in Depo-Provera), cyproterone acetate (found in Dianette), and nomegestrol acetate (found in Zoely)—have been associated with a higher risk of developing meningiomas. Notably, the risk appears to be dose-dependent, with prolonged use increasing the likelihood of tumor development. It's important to note that while these associations exist, the overall risk remains low, and more research is needed to fully understand the relationship between progesterone use and meningioma development. Women using these medications should consult with their healthcare providers to discuss potential risks and consider alternative options if necessary.
Cycle mapping - how best to monitor your menstrual cycle
Cycle mapping involves tracking key female hormones—LH, FSH, estradiol, and progesterone—throughout your menstrual cycle to assess ovulation and hormone patterns. Unlike traditional single-point blood tests, cycle mapping provides a comprehensive view, especially beneficial for those with irregular cycles, perimenopausal symptoms, or fertility concerns. Utilizing advanced tools like the Mira hormone monitor, which offers real-time, quantitative data, can enhance accuracy in tracking hormonal fluctuations. This approach aids in identifying ovulation timing, luteal phase length, and menopausal progression, facilitating informed healthcare decisions.
Berberine for PCOS
Berberine could help lower testosterone levels and the LH to FSH ratio compared to a placebo or no treatment.
The role of the microbiome in phytoestrogens
The gut microbiome plays a crucial role in metabolising phytoestrogens—plant-derived compounds found in foods like soy, flaxseeds, and legumes. These compounds can mimic estrogen in the body, potentially alleviating menopausal symptoms and supporting hormonal balance. However, their effectiveness depends on the composition of an individual's gut bacteria. Certain gut microbes are better equipped to convert phytoestrogens into bioactive forms that the body can utilise. A diverse and healthy microbiome enhances this conversion, while an imbalanced microbiome may reduce efficacy. Factors such as diet, antibiotic use, and lifestyle choices can influence gut health and, consequently, the benefits derived from phytoestrogens. Maintaining a balanced microbiome through a fiber-rich diet, probiotics, and prebiotics may optimise the health benefits of phytoestrogens.
The Gut Microbiome and Cardiovascular Health
Diet plays a crucial role in cardiometabolic health, influencing both the composition of the microbiome as well as the development of related diseases. The gut microbiome, in particular, has been found to contribute to conditions such as hypertension, obesity, and diabetes through its impact on inflammation, insulin sensitivity, and blood lipid levels. A healthy gut microbiome is one that promotes long-term stability, resists infection, and helps the host maintain metabolic and immune balance.
Anastrazole for breast cancer prevention
Anastrazole has a license for the prevention in post-menopausal women with a moderate of high risk of developing breast cancer
Metformin & PCOS
Sirona Health is pleased to share the latest evidence-based recommendations for managing Polycystic Ovary Syndrome (PCOS) using Metformin.
Painful periods since adolescence
Painful periods should be a call to action to improve the overall health status of the young woman suffering on a monthly basis
Non-steroidal painkillers and the ‘pill’ - new evidence of blood clot risk
Taking NSAIDs like ibuprofen with combined oral contraceptives (the pill) may increase the risk of blood clots (VTE). Studies suggest this combination can raise the risk significantly. If you’re on the pill, it’s safer to use paracetamol for pain relief and consult your healthcare provider before using NSAIDs—especially if you have additional risk factors like obesity or a history of clots.