Identifying Hormone Patterns — Progesterone Decline During the Menopausal Transition
As ovulation slows in midlife, progesterone production drops—often leaving estrogen unopposed. The result? Heavy periods, mood swings, and hormonal imbalance. Learn why progesterone matters in perimenopause and how tracking your hormones with Mira can help you take control.
Testosterone Cream for Postmenopausal Women Now Licensed in the UK
The MHRA has approved a testosterone cream for postmenopausal women in the UK. At Sirona Health, based in Bath, Stroud, Cirencester & Tetbury, you can access this treatment privately now — even before the official UK launch.
Zoely & PMDD: Could This Pill Help Ease Your Symptoms?
Discover how Zoely — a contraceptive pill containing nomegestrol acetate and bioidentical estradiol — may help ease PMDD symptoms. Learn the science, benefits, and how it compares with other pills, so you can make an informed decision about your treatment.
Clinical Insights on Hormonal Monitoring with Mira and Its Role in Perimenopause Management
Discover how Mira hormonal monitoring provides real-time insights into the fluctuating hormone levels during perimenopause. Learn how this advanced tool helps personalise treatment plans, improve symptom management, and guide effective hormone replacement therapy.
Is HRT Right for Me? How Mira Helps Make That Decision Easier
Navigating hormone therapy decisions can be complex. Mira's hormone tracking technology offers personalised insights into your hormonal patterns, helping identify whether estrogen, progesterone, or other factors are contributing to your symptoms. This data empowers you and your healthcare provider to make informed, tailored decisions about HRT, ensuring a treatment plan that aligns with your unique hormonal profile. Discover how Mira can guide you through this important decision-making process.
How the Mira Monitor Can Help You Understand Your Hormone Chaos
Experiencing fatigue, bloating, or mood swings despite normal blood tests? The Mira monitor tracks key hormones—LH, E3G, PdG, and FSH—through daily urine samples, revealing patterns like estrogen dominance or low progesterone. This data helps pinpoint ovulatory cycles and hormonal imbalances, offering clarity during perimenopause. At Sirona Health, we interpret your Mira results in the context of your symptoms, guiding decisions on HRT, supplements, and lifestyle interventions.
Why Perimenopause Feels So Confusing and What You Can Do About It
Are your periods suddenly unpredictable? Mood swings or brain fog creeping in? You’re not imagining it—and you’re not alone. Perimenopause is a hormonal rollercoaster, with fluctuating cycles, sleep issues, anxiety, fatigue, and weight changes—yet a single blood test often misses the bigger picture. At Sirona Health, we use the Mira hormone monitor to track estrogen, LH, FSH, and progesterone levels over time. That way, we can decode how your hormones relate to your symptoms and tailor personalised advice—so you stop guessing and start understanding what’s happening in your body.
Navigating the Decision to Stop HRT: What We Know — and What We Still Don’t
Thinking about stopping HRT? At Sirona Health, we know there’s no one-size-fits-all answer. While HRT offers relief from symptoms like hot flushes and brain fog, the decision to stop depends on your age, symptom severity, and health risks. And with up to 40% of women experiencing a return of symptoms—some restarting HRT later—making the timing and method right is key. Learn what current guidelines say, why research gaps remain, and how we can support you in making a confident, personalised choice.
Understanding Progesterone and Progestogens: What You Need to Know
Progesterone is a vital hormone that plays a key role in regulating the menstrual cycle, preparing the body for implantation, and maintaining a healthy pregnancy. During perimenopause, progesterone levels fluctuate, leading to symptoms like irregular periods, mood swings, and sleep disturbances. Understanding these changes and how to manage them is crucial for women's health during this transitional phase. Explore how monitoring progesterone levels can provide insights into your health and guide effective treatment strategies.
Progesterone and the gut
Progesterone, often associated with reproductive health, also plays a crucial role in gut health. It modulates immune responses and gastrointestinal function, influencing conditions like irritable bowel syndrome (IBS). Fluctuations in progesterone levels, particularly during perimenopause and menopause, can exacerbate digestive symptoms such as bloating, abdominal pain, and irregular bowel movements. Understanding this connection is vital for managing gut health during hormonal transitions.
HRT & Weight Loss Injections: What You Need to Know
Combining hormone replacement therapy (HRT) with weight loss injections like semaglutide (Wegovy, Ozempic) or tirzepatide (Mounjaro) is increasingly common. However, recent guidance from the British Menopause Society highlights potential interactions: these medications can slow digestion, possibly reducing the absorption of oral progesterone, a key component of HRT. This may compromise endometrial protection, especially for women with a uterus. Alternative progesterone delivery methods, such as the Mirena coil or combined HRT patches, are recommended. It's crucial to consult with a healthcare provider to adjust your treatment plan accordingly.
Brain Fog in Women: What’s Happening During Pregnancy and Menopause?
Experiencing forgetfulness, difficulty concentrating, or mental fatigue? These are common symptoms of brain fog, particularly during pregnancy and menopause. Hormonal fluctuations, such as changes in estrogen and progesterone levels, can impact brain function, leading to cognitive challenges. While these symptoms are often temporary, they can be managed through lifestyle adjustments, including adequate sleep, stress management, and a balanced diet. In some cases, hormone replacement therapy (HRT) may offer relief. It's important to consult with a healthcare provider to determine the best approach for your individual needs.
Feeling Constantly Tired? Let’s Talk About Fatigue
Fatigue is a common yet often overlooked symptom among women, particularly in their 40s and 50s. It's more than just feeling tired—it's a persistent, overwhelming exhaustion that isn't relieved by sleep. This chronic fatigue can significantly impact daily life and may be linked to various factors such as hormonal changes during perimenopause and menopause, iron deficiency, thyroid dysfunction, psychological stress, sleep disorders, and nutritional deficiencies. Understanding the underlying causes is crucial for effective management and treatment. Explore how addressing these factors can help restore your energy and well-being.
The Non-Contraceptive Benefits of Zoely: What Women in the UK Should Know
Zoely isn’t just a reliable contraceptive — it’s a powerful ally for your overall health. From lighter, more manageable periods to clearer skin and relief from PMS symptoms, this unique estradiol and nomegestrol pill offers benefits far beyond pregnancy prevention. Discover how Zoely can support your menstrual health, boost your well-being during perimenopause, and help you feel more in control of your cycle.
Anti-Mullerian Hormone - AMH
Anti-Müllerian Hormone (AMH) is a key indicator of ovarian reserve, reflecting the quantity of a woman's remaining eggs. While AMH levels naturally decline with age, they can provide valuable insights into reproductive health. In perimenopause and menopause, AMH testing can help assess the timing of ovarian decline and inform decisions about fertility preservation or hormone replacement therapy (HRT). However, AMH levels should be interpreted cautiously, as they do not account for egg quality or guarantee fertility outcomes. It's essential to consult with a healthcare provider to understand what AMH levels mean for your individual health journey.