When Standard PMDD Treatments Aren't Enough: Is There a Role for Antipsychotic Medication?
PMDD, Treatment & Management, Medical treatments Georgina Standen PMDD, Treatment & Management, Medical treatments Georgina Standen

When Standard PMDD Treatments Aren't Enough: Is There a Role for Antipsychotic Medication?

Most women with PMDD improve with SSRIs or hormonal treatment, but some continue to experience severe symptoms. This article explores the emerging evidence for antipsychotic medication as a specialist treatment option in treatment-resistant PMDD.

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SSRIs, SNRIs and Mirtazapine: Choosing the Right Antidepressant for Hormone-Sensitive Mood Disorders
PMDD, Medical treatments, Treatment & Management Georgina Standen PMDD, Medical treatments, Treatment & Management Georgina Standen

SSRIs, SNRIs and Mirtazapine: Choosing the Right Antidepressant for Hormone-Sensitive Mood Disorders

A major Lancet study published in 2025 has highlighted how antidepressants differ in their physical effects — from weight and blood pressure to heart rate and sleep. For women managing hormone-linked mood disorders such as PMDD, postnatal depression, or perimenopausal anxiety, understanding these differences can help guide safer, more personalised treatment choices.

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Vitex agnus-castus (Chasteberry) and PMS: Can Nature Support Your Hormonal Health?

Vitex agnus-castus (Chasteberry) and PMS: Can Nature Support Your Hormonal Health?

Vitex agnus-castus (chasteberry) is one of the most researched herbal options for PMS and PMDD, helping to balance prolactin and support the natural rhythm of oestrogen and progesterone. In this article, Dr Georgina Standen explains how Vitex works, what the latest evidence shows, who it’s suitable for, and how to use it safely—alone or alongside conventional treatments—to support mood, cycle regularity and premenstrual wellbeing.

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The Future of PMDD Treatment: Neuroactive Steroids
PMDD, Treatment & Management, Medical treatments Georgina Standen PMDD, Treatment & Management, Medical treatments Georgina Standen

The Future of PMDD Treatment: Neuroactive Steroids

New research is changing how we understand and treat PMDD. Instead of suppressing hormones, emerging treatments known as neuroactive steroids work by calming the brain’s response to hormonal change. Here, Dr Georgina Standen explains how brexanolone and zuranolone work, what current evidence shows, and what this could mean for women in the UK.

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